Engineering Solutions • Packaging
Formulation Effervescent Packaging Containment Transfer Systems

Complete Integrated Pharmaceutical Packaging Solutions

At Mark Maker Engineering, we provide integrated packaging solutions designed to meet the evolving requirements of pharmaceutical manufacturing. Our packaging systems combine reliable primary packaging technology with flexible automation and downstream integration to create efficient, coordinated and production-ready packaging lines.

Our EFF Pack range provides the core packaging platform, while ancillary machines can be integrated according to the required packaging configuration, production speed and automation level.

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50 to 150+ Tubes / Min
Servo Precision Counting
Hermetic Capping & Desiccant
cGMP & 21 CFR Part 11
Core Packaging Platform

EFF Pack 100 System

EFF Pack 100 Tube Filling and Packaging Machine
Output Capacity Up to 100 Tubes/min
Tablet Counting Multi-Track Optical Servo
Closure Method Hermetic Desiccant Plug
Line Integration Turnkey Upstream/Downstream

Packaging Portfolio

Complete Packaging Equipment Portfolio

From core EFF Pack tube filling machinery to downstream vision verification, labelling, check weighing and automated cartoning, our equipment works as a synchronized, high-efficiency packaging line.

STAGE 01 Core Primary Packaging
EFF Pack 50 Compact Packaging Machine
Compact Footprint Up to 50 Tubes/min

EFF Pack 50

A compact packaging solution designed for applications requiring efficient and controlled packaging performance with a focus on flexibility and ease of operation. Ideal for pilot facilities, regional batches, and clinical manufacturing.

Available Models & Configurations
EFF Pack 50 Standard → Quick-Changeover Tooling Single-Track Infeed
  • Compact cleanroom footprint engineered for space-constrained suites
  • Accurate mechanical and optical counting channels with gentle tablet chutes
  • Integrated automatic tube feeding and desiccant cap press insertion
  • Tool-less changeover between different tube diameters and tablet counts
STAGE 02 High-Throughput Packaging
EFF Pack 100 High-Speed Tube Filling Machine
Servo Precision Up to 100 Tubes/min

EFF Pack 100

Designed for higher production requirements, providing increased throughput while maintaining controlled and consistent packaging operations. Features multi-track servo tablet feeding and dual-station rotary indexing for rapid, reliable packaging.

Available Models & Configurations
EFF Pack 100 High-Speed → Dual Rotary Indexer Multi-Track Servo Infeed
  • High-speed multi-channel tablet counting with optical verification sensors
  • Dual-station rotary indexing turret for smooth container stabilization
  • Vibratory desiccant cap sorter with pneumatic pressing ram
  • Integrated no-tube/no-fill and missing desiccant detection interlocks
STAGE 03 Continuous Industrial Output
EFF Pack 150 High-Capacity Machine
Maximum Speed 150+ Tubes/min

EFF Pack 150

A higher-capacity packaging solution developed for demanding continuous production environments where maximum output and complete automation are required. Seamlessly links upstream tablet presses to downstream continuous cartoners.

Available Models & Configurations
EFF Pack 150 Continuous High-Speed Buffer Infeed Twin Rotary Capper
  • Continuous-motion indexing system engineered for heavy-duty 24/7 manufacturing
  • High-frequency vibratory bowl sorting with automated desiccant cap feeding
  • Dual servo pick-and-place capper with electronic torque control
  • Real-time OEE reporting, diagnostic monitoring, and centralized SCADA connectivity
STAGE 04 Flexible Semi-Automation
EFF Pack Semi-Automatic Tube Packaging Machine
Rapid Format Switch Semi-Automatic

EFF Pack S.A.

An advanced packaging configuration designed for applications requiring enhanced semi-automation, rapid format switching, and easy integration within specialized pharmaceutical suites or multi-product facilities.

Available Models & Configurations
EFF Pack S.A. Standalone → Benchtop Configuration Ergonomic Tray Loader
  • Semi-automated tube loading with motorized counting and auto-discharge chute
  • Fast format changeover (< 15 minutes) accommodating varied tube sizes
  • cGMP SS 304 external cladding with SS 316 product contact parts
  • Dual optical safety curtains and ergonomic operator loading positions
STAGE 05 Quality Assurance
High-Speed Vision Inspection System
100% In-Line Verification Optical / OCR

Vision Inspection Systems

High-speed industrial machine vision systems verifying tablet count, tablet surface integrity, cap seating height, and 2D DataMatrix code legibility. Automatically identifies and rejects defective packs without reducing line throughput.

Available Models & Configurations
In-Chute Tablet Inspection 360° Cap Position Verifier OCR Serialization Checker
  • High-resolution cameras verifying tablet color, thickness, and chipped edge defects
  • Pneumatic air-blast or push-arm rejection mechanism for defective containers
  • Failsafe locked reject bin with bin-full and reject-confirmation sensors
  • 21 CFR Part 11 compliant audit trail, rejected image archiving, and defect analytics
STAGE 06 Serialization & Coding
Printing and Coding Serialization Unit
TIJ / Laser / CIJ GS1 DataMatrix

Printing & Coding Systems

Integrated Thermal Inkjet (TIJ) and laser coding technologies configured for sharp batch coding, expiry dates, and serialization codes on tube bodies, bottoms, and carton flaps at continuous line speeds.

Available Models & Configurations
Thermal Inkjet (TIJ) Station CO2 / Fiber Laser Marker Continuous Inkjet (CIJ)
  • High-resolution 600 DPI printing on aluminum, plastic tubes, and cardboard
  • Fast-drying pharmaceutical solvent inks resistant to wipe-off and handling
  • Full compatibility with serialization software and track-and-trace architectures
  • In-line barcode grading verifying readability against ISO/IEC standards
STAGE 07 Labelling & Check Weighing
Automatic Labelling Machine
Wrap-Around Accuracy Dynamic ±0.1g

Labelling & Check Weighing

High-precision automatic wrap-around labelling systems paired with dynamic in-line check weighers to ensure 100% compliant weight verification and flawless aesthetic presentation for cylindrical pharmaceutical tubes.

Available Models & Configurations
Rotary Wrap Labeller Linear Starwheel Labeller Dynamic Check Weigher
  • Servo-driven dispensing head delivering accurate, wrinkle-free wrap application
  • High-speed load cells providing dynamic weight checks with rapid pneumatic reject
  • Automatic label run-out alarms and dual-spindle unwind for continuous operation
  • Tamper-evident seal and hologram application options
STAGE 08 Secondary & End-of-Line
Cartoning and End of Line Packaging Integration
Continuous Motion Case Pack & Bundle

Cartoning & End-of-Line

Complete secondary packaging integration including horizontal continuous cartoners with pre-folded leaflet insertion, tamper-evident tuck or hot-melt closure, multi-pack bundlers, and automated case packers.

Available Models & Configurations
Horizontal Continuous Cartoner Intermittent Cartoner Case Packer & Bundler
  • Synchronized tube transfer from labelling conveyor directly into cartoner buckets
  • Automated leaflet inserter supporting flat-sheet folding or pre-folded inserts
  • Hot-melt glue closure or tuck-in flaps with integrated carton embossing
  • Automated end-of-line case erection, loading, and top/bottom tape sealing

Coordinated Line Engineering

Complete Packaging Line Integration

A packaging machine is only one part of the complete production line. At Mark Maker Engineering, we integrate suitable ancillary equipment around the EFF Pack system to develop a coordinated packaging line based on the customer’s product, process and production requirements.

Our engineering approach allows individual packaging and ancillary machines to operate as a coordinated system rather than independent units:
Primary Packaging → Printing / Coding → Vision Inspection → Labelling → Check Weighing → Cartoning → End-of-Line Packaging

This integrated approach helps streamline material flow, reduce manual intervention and provide seamless coordination between individual packaging stages.

01

Speed Synchronization & Buffering

Smart line conveyors and accumulator buffers prevent line throttling, automatically modulating speed between filling, capping, labelling, and cartoning.

02

Failsafe Vision & Rejection

In-line optical cameras verify tablet count, desiccant cap depth, and coding at full speed, instantly diverting non-conforming items into secure bins.

03

Supervisory Line Connectivity

Centralized PLC/HMI architecture tracking real-time line speed, Overall Equipment Effectiveness (OEE), scrap rates, and 21 CFR Part 11 electronic batch logs.

04

Single Turnkey Partner

One experienced engineering team provides comprehensive line design, factory acceptance testing (FAT), site commissioning, and validated qualification (DQ/IQ/OQ).

Core Standards

Engineered for Packaging Excellence

Every packaging machine is manufactured to meet rigorous pharmaceutical manufacturing guidelines, prioritizing tablet integrity, cleanroom hygiene, and maximum line uptime.

Gentle Tablet Handling

Smooth feed channels and soft deceleration chutes prevent chipping, dusting, or breakage of delicate effervescent tablets.

Hermetic Desiccant Capping

Precise vertical cap ramming ensures complete desiccant stopper seating, maintaining moisture protection throughout shelf life.

Rapid Tool-Less Changeovers

Quick-release starwheels and snap-in guide tracks allow format changeovers in under 30 minutes, minimizing line downtime.

cGMP Stainless Steel Construction

SS 304 external cladding with certified SS 316 / anodized aluminum for all product and tube contact surfaces.

100% In-Line Defect Rejection

Integrated verification sensors track count, cap insertion, and coding, with zero non-compliant items escaping to downstream stations.

21 CFR Part 11 Electronic Records

Touchscreen HMI interfaces equipped with multi-level password protection, audit trails, and automated batch report generation.

Custom Pack Architecture

Tailored engineering for unique tube geometries, varying tablet thicknesses, dual-stack configurations, and special cap profiles.

Comprehensive Validation Support

Full Design Qualification (DQ), Installation (IQ), and Operational Qualification (OQ) protocols tailored for international audits.

Engineered Packaging Lines

Designed Around Your Packaging Requirements

Every pharmaceutical packaging application has different requirements. Product format, pack configuration, output, inspection criteria, coding requirements and downstream handling can significantly influence line design.

Mark Maker Engineering works with customers to develop packaging configurations tailored around these specific parameters — from the core EFF Pack machine to downstream inspection, labelling, cartoning and end-of-line handling.

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Technical Matrix

Packaging Equipment Overview

Quick reference specifications across our packaging equipment series, capacity metrics, and automation configurations.

Equipment Models Available Capacity / Speed Core Mechanism Contact Metallurgy
EFF Pack 50 Tube Filler EFF Pack 50 Standard Up to 50 tubes/min Single-track counting & pneumatic cap press SS 316 / Anodized Al
EFF Pack 100 High-Speed EFF Pack 100 Multi-Track Up to 100–120 tubes/min Servo multi-track counter & rotary indexer SS 316 / SS 304
EFF Pack 150 Industrial EFF Pack 150 Continuous Up to 150 tubes/min Continuous-motion indexing & twin capper SS 316 / SS 304
EFF Pack Semi-Automatic EFF Pack S.A. Benchtop 20 – 35 tubes/min Semi-automatic loading with optical count SS 316 / SS 304
Vision Inspection Unit VIS-100 / VIS-150 Synchronized to line Cognex/Keyence optical tablet & cap verifier SS 304 Cleanroom
Wrap-Around Labeller WRL-80 / WRL-150 Up to 150 tubes/min Servo dispensing with rotary wrapping belt SS 304 / Hardened Al
Dynamic Check Weigher CW-120 In-Line Up to 120 tubes/min (±0.1g) High-frequency load cell with pneumatic reject SS 304 Cleanroom
Continuous Cartoner CART-100 / CART-150 Up to 150 cartons/min Continuous rotary carton feed & leaflet folder SS 304 / Sanitary alloys

Packaging Solutions by Mark Maker Engineering

Pack. Inspect. Label. Carton. Integrate.

One packaging partner. Complete line. Talk to our technical team to configure a standalone EFF Pack machine or a fully integrated packaging line for your pharmaceutical facility.

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