Pharmaceutical Solutions

Precision Machinery Across Process Disciplines

Explore our validated solid dosage lines, isolation safety boxes, and cleanroom material transfer suites engineered to comply with FDA, cGMP, and OEB guidelines.

Effervescent Processing System (EFF-PRO)

Effervescent Processing System (EFF-PRO)

Closed-system fluid bed granulation and drying platform engineered specifically for moisture-reactive effervescent formulations.

Tube Filling Machine (EFF-PACK)

Tube Filling Machine (EFF-PACK)

High-speed automated packaging line engineered for precise tablet counting, rigid tube insertion, desiccant cap feeding, and hermetic sealing.

Vacuum Tray Dryer (VTD)

Vacuum Tray Dryer (VTD)

Gentle low-temperature vacuum drying for sensitive active pharmaceutical ingredients, thermolabile powders, and hygroscopic materials.

Air Tray Dryer (ATD)

Air Tray Dryer (ATD)

cGMP convective recirculating air dryer designed for uniform thermal distribution across multiple precision stainless steel trays.

Integrated Wet Granulation

Integrated Wet Granulation

End-to-end closed granulation train integrating rapid high-shear mixing, wet sizing, fluid bed drying, and dry milling.

Rapid Mixer Granulator (RMG)

Rapid Mixer Granulator (RMG)

High-shear mixer designed for rapid, homogeneous dry blending and wet granulation with dual impeller and chopper tooling.

Fluid Bed Dryer (FBD)

Fluid Bed Dryer (FBD)

High-thermal efficiency dryers engineered for uniform fluidization, precise temperature profiling, and moisture control in wet granulates.

Auto Tablet Coater (AC)

Auto Tablet Coater (AC)

Automated tablet film and sugar coating system with perforated pan configuration, anti-bearding spray guns, and intelligent recipe control.

Extruder

Extruder

High-precision screw extrusion unit producing uniform, dense cylindrical extrudates from moist powder blends for multi-particulate drug delivery.

Spheronizer

Spheronizer

Centrifugal friction-plate spheronizing unit transforming cylindrical extrudates into high-sphericity pellets with narrow particle size distribution.

Fluid Bed Coater (FBC)

Fluid Bed Coater (FBC)

Wurster bottom-spray precision coating system engineered for controlled-release pellet coating, micro-encapsulation, and enteric layering.

Conta Pillar Blender (CPB)

Conta Pillar Blender (CPB)

Single-pillar tumble blender designed for dust-tight batch blending of pharmaceutical IPC bins with 360-degree rotational tumbling.

Octagonal Blender (OCB)

Octagonal Blender (OCB)

Gentle blending action using octagonal geometry and internal baffles, ideal for fragile crystals, granulates, and lubrication blending.

Double Cone Blender (DCB)

Double Cone Blender (DCB)

Conical vessel geometry ensuring rapid, uniform axial and cross-flow mixing of free-flowing dry powders and granules.

V Cone Blender (V-Blender)

V Cone Blender (V-Blender)

V-shaped shell blenders providing continuous split and recombine action for high-accuracy blending of sensitive pharmaceutical dry powders.

Multi Attached Blender

Multi Attached Blender

Versatile modular drive system accommodating multiple interchangeable mixing vessels including V, octagonal, and double cone geometries.

Granulator Isolator

Granulator Isolator

Sealed barrier environments enclosing rapid mixer granulators and sizing mills for OEB 4/5 high-potency API processing.

Barrier Isolator

Barrier Isolator

Rigid-wall containment barrier with validated gloveports, HEPA laminar filtration, and rapid transfer ports for operator protection.

Restricted Access Barrier Systems (RABS)

Restricted Access Barrier Systems (RABS)

Open and closed RABS enclosures providing ISO 5 cleanroom conditions and physical barriers for aseptic and toxic compounding suites.

Laminar Flow Enclosures

Laminar Flow Enclosures

Vertical and horizontal laminar airflow workstations ensuring uni-directional sterile protection for sampling and dispensing operations.

Glovebox Systems

Glovebox Systems

Hermetically sealed glovebox suites with negative/positive pressure cascades and inert gas purging for hazardous active compounds.

Process Equipment Isolators

Process Equipment Isolators

Tailor-engineered containment interfaces enclosing tablet presses, capsule fillers, coaters, and fluid bed discharge ports.

Decontainment Isolators

Decontainment Isolators

WIP/CIP integrated decontainment chambers for safe neutralization, bag-out, and cleaning of toxic powder residue before opening.

Powder Transfer Systems (PTS)

Powder Transfer Systems (PTS)

Dense-phase vacuum pneumatic powder transport systems designed for dust-free, closed transfer across process suites and floors.

IPC Bin Container

IPC Bin Container

Pharmaceutical-grade SS 316L Intermediate Process Containers (IBC) with sanitary butterfly valves for zero-leakage storage and transfer.

Lifting & Tilting Device (LTD)

Lifting & Tilting Device (LTD)

Heavy-duty electro-hydraulic lifting and tilting units for high-level discharge of IBC bins and containers into hoppers and coaters.

Lifting & Positioning Device (LPD)

Lifting & Positioning Device (LPD)

Precision hydraulic column lifts designed for ergonomic vertical positioning, docking, and charging of blenders, granulators, and mills.

Dry Co Mill (DCM)

Dry Co Mill (DCM)

Conical screen mill engineered for low-energy particle de-agglomeration, gentle sizing, and uniform granulation without heat buildup.

Multi Mill (MML)

Multi Mill (MML)

High-speed multi-blade milling and comminuting unit for fine wet/dry pulverization, shredding, and controlled size reduction.

Paste Preparation Vessel (PPV)

Paste Preparation Vessel (PPV)

Steam/electrically jacketed sanitary preparation kettle with anchor agitator and Teflon scrapers for uniform binder solution preparation.

Vibro Sifter (VSFT)

Vibro Sifter (VSFT)

High-amplitude gyratory circular screening sifter for grading, dedusting, and classifying dry powders and pharmaceutical granules.

Turnkey Engineering

Bespoke Custom Engineering

Every pharmaceutical, fine chemical, and food processing facility presents unique architectural, ergonomic, and cleanroom requirements. At MarkMaker, we don't just supply individual units; we engineer integrated, end-to-end processing skids, containment isolators, and automated material transfer trains custom-tailored to your exact cleanroom footprint.

  • check_circle Tailored facility-to-machine footprint optimization & 3D cleanroom modeling
  • check_circle Custom 21 CFR Part 11 automation workflows, recipes & SCADA integration
  • check_circle Specialized metallurgy (SS 316L, Hastelloy C-22) for corrosive active ingredients
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